NIDA CTN-0099: Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION)

This study will evaluate implementation of emergency department (ED)-initiated BUP in a large number of sites; compare extended release (XR)-BUP with sublingual (SL) BUP in ED patients with untreated OUD; and develop and validate electronic health record phenotypes of opioid-related illnesses to characterize ED visits, enhance active disease surveillance, and better identify patients eligible for study inclusion.

Part of the National Institute on Drug Abuse Clinical Trials Network. The Addictions, Drug & Alcohol Institute serves as the Regional Research and Training Center (RRTC) of the Pacific Northwest Node, which participated in this protocol.

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