Addictions, Drug & Alcohol Institute

NIDA CTN-0031: Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement

The primary objective of this protocol is to evaluate the degree to which a combined group and individual 12-Step facilitative intervention, Stimulant Abuser Groups to Engage in 12 -Step (STAGE-12), improves substance -related outcomes compared to treatment as usual (TAU) without STAGE-12 among stimulant abusers.  For this protocol, STAGE-12 will be integrated into treatment as usual.  The primary objective is to evaluate reduction in percent of days of stimulant use as measured by self-report.  This is a randomized, 2-group design comparing STAGE-12 integrated into TAU (STAGE-12 /TAU) to TAU without STAGE-12 for stimulant abusers receiving formal substance abuse treatment in participating community-based treatment programs (CTP).  A total of approximately 450 stimulant users seeking formal treatment, recruited from 10 CTPS, will be randomized.

Part of the National Institute on Drug Abuse Clinical Trials Network. The Alcohol & Drug Abuse Institute serves as the Regional Research and Training Center (RRTC) of the Pacific Northwest Node. The Pacific Northwest Node was Co-Lead Node on this project.


Dennis M. Donovan, PhD Co-Lead Investigator (UW ADAI)
Dennis Daley, PhD Co-Lead Investigator (Western Psychiatric Institute and Clinic)

Project Staff

Mary Hatch-Maillette, PhD

Fund Information

National Institute on Drug Abuse (NIDA)
Start: January 2008
End: April 2010
Status: completed

Project Site

CTN Dissemination Library protocol page for CTN-0031

Project Results

Findings were mixed with respect to the impact of integrating the STAGE-12 intervention into intensive outpatient drug treatment compared with treatment as usual on stimulant drug use. However, the results more clearly indicate that individuals in STAGE-12 had higher rates of 12-step meeting attendance and were engaged in more related activities throughout both the active treatment phase and the entire 6-month follow-up period than did those in treatment as usual.

Citation: Donovan DM, et al. Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): A Multisite Trial in the National Institute on Drug Abuse Clinical Trials Network. Journal of Substance Abuse Treatment 2012;44(1):103-114. [free online]