Addictions, Drug & Alcohol Institute

NIDA CTN-0048: Cocaine Use Reduction with Buprenorphine (CURB)

The aim of this study is to investigate the safety and effectiveness of buprenorphine in the presence of naltrexone for the treatment of cocaine dependence. Eleven CTP study sites will enroll 300 cocaine-dependent participants who also meet criteria for either past-year opioid dependence or past-year opioid abuse, or past-year opioid use with a history of opioid dependence during the lifetime.


Walter Ling, MD Lead Investigator (UCLA)
Andrew Saxon, MD Co-Lead Investigator (VA Puget Sound)
Larissa Mooney, MD Co-Lead Investigator (UCLA)

Fund Information

Status: completed