Center for Neuroregulation in Alcohol Dependence (CeNiAD)

The Developmental Center for Neuroregulation in Alcohol Dependence (CeNiAD) grew from the clinical observation that the CNS active generic alpha-one adrenoreceptor (AR) antagonist prazosin reduced or eliminated alcohol drinking in veterans with posttraumatic stress disorder (PTSD) and comorbid alcohol dependence. Goals for this project were to create an interdisciplinary translational research team investigating alpha-one adrenergic receptor (AR) and other neuroregulatory mechanisms and interventions in alcohol use disorders (ADD); and (2) To establish the collaborations, facilities, research capabilities, preliminary findings, career development opportunities, intellectual milieu and planning process to justify an application for a future new Specialized P50 Alcohol Research Center.

Dr. Donovan served as a member of the executive committee and provided input on all aspects of CeNiAD research, training, and center development.

---